Plenary Lecture

  • Plenary Lecture

    • Jeffrey Friedman (Laboratory of Molecular Genetics, Rockefeller University, USA)
    • Lecture Date & Time : May 25 (Tue), 15:30-16:10, Room 101~104, 106~109
    • Title: Leptin and the Homeostatic Control of Body Weight
    [Biography]
    Dr. Jeffrey Friedman isolated leptin, an adipocyte hormone that regulates food intake and body weight in animals and human. Leptin mutations cause severe obesity and treatment with leptin corrects the obesity in these patients. Leptin is also an approved treatment for lipodystrophy, a severe metabolic disorder.
    After completing medical school and internal medicine training, Dr. Friedman entered The Rockefeller University graduate program and was awarded a Ph.D. degree in 1986 prior to joining the Rockefeller Faculty. Friedman is currently a Professor at the Rockefeller University, and an Investigator at the Howard Hughes Medical Institute.
    Dr. Friedman has recently received the 2019 Breakthrough Prize and 2019 Wolf Prize. He also shared the 2010 Albert Lasker Award for Basic Medical Research with Douglas Coleman for the discovery of leptin. He was elected to the National Academy of Science (2001) from which he received the Kovalenko Medal. He has received the Gairdner International Award (2005), Keio Medical Science Prize (2009), Shaw Prize (2009), BVA Prize (2012) and an honorary degree from Yale University (2015), among others. He is Foreign Member of the Royal Society (2018) and a member of National Academy of Sciences (United States).
    His current research laboratory is aimed at understanding the genetic basis of obesity in human and the neural mechanisms by which leptin regulates appetite and metabolism.
  • Plenary Lecture

    • Muzlifah Haniffa (Newcastle University, UK)
    • Lecture Date & Time : May 25 (Tue), 16:10-16:50, Room 101~104, 106~109
    • Title: Decoding the developing human immune system
    [Biography]
    Muzlifah Haniffa is a Wellcome Trust Senior Research Fellow, Lister Institute Research Fellow and Consultant Dermatologist based in Newcastle University. She graduated from medical school in Cardiff, trained as a junior doctor in Cambridge and received her dermatology specialist training in Newcastle. She was awarded an Action Medical Research Training Fellowship and a Wellcome Trust Clinical Intermediate Fellowship.
    Muzlifah is a Fellow of the Academy of Medical Sciences (2020) and the recipient of the Academy of Medical Sciences Foulkes Foundation Medal (2019) and the European Federation of Immunological Societies ACTERIA Prize in Immunology and Allergology (2018). She is a leading member of the Human Cell Atlas initiative and pioneered the application of single cell genomics to decode the developing human immune system, and the human skin in health and disease.
  • Plenary Lecture

    • Stephen J. Simpson (The University of Sydney, Australia)
    • Lecture Date & Time : May 26 (Tue), 15:30-16:10, Room 101~104, 106~109
    • Title: The Nutritional Geometry of Aging and Metabolic Health
    [Biography]
    Steve Simpson is the inaugural Academic Director of the Charles Perkins Centre and Professor in the School of Life and Environmental Sciences at the University of Sydney. The Charles Perkins Centre is a major initiative aimed at easing the burden of chronic disease through innovative, multidisciplinary research and education.
    After graduating as a biologist from the University of Queensland, Steve undertook his PhD at the University of London, then spent 22 years at Oxford before returning to Australia in 2005 as an Australian Research Council Federation Fellow, then ARC Laureate Fellow.

    Steve and David Raubenheimer have developed an integrative modelling framework for nutrition (the Geometric Framework), which was devised and tested using insects and has since been applied to a wide range of organisms, from slime moulds to humans, and problems, from aquaculture and conservation biology to the dietary causes of human obesity and ageing. He has also pioneered understanding of swarming in locusts, with research spanning neurochemical events within the brains of individual locusts to continental-scale mass migration.

    In 2007 Steve was elected a Fellow of the Australian Academy of Science, in 2013 he was elected a Fellow of the Royal Society of London, and in 2015 was made a Companion of the Order of Australia.
  • Plenary Lecture

    • Juergen Knoblich (IMBA – Institute of Molecular Biotechnology, Vienna, Austria)
    • Lecture Date & Time : May 26 (Tue), 16:10-16:50, Room 101~104, 106~109
    • Title: Using cerebral organoids to discover human-specific mechanisms of brain development
    [Biography]
    Juergen Knoblich’s laboratory is interested in the biology of neural stem cells. In the fruitfly, they have identified the molecular mechanism that allows neural stem cells to segregate protein determinants into only one daughter cell during mitosis and to divide asymmetrically. They have demonstrated that defects in this mechanism lead to brain tumor formation. More recently, they have extended their interest to analyzing mammalian neural progenitors and their contribution to brain development. To analyze those processes in humans, they have established a 3D culture system that recapitulates the early steps of human brain development in cell culture allowing brain pathologies and human specific developmental events to be studied in unprecedented detail. In particular, they have used this system for modelling microcephaly thereby demonstrating for the first time that human neurodevelopmental disorders can be studied in 3D culture.
    Jürgen Knoblich started his scientific career as a graduate student at the Max Planck Institute in Tübingen where he worked on cell cycle control in Drosophila under the guidance of Christian Lehner. In 1994 he moved to San Francisco to join the laboratory of Yuh Nung and Lily Jan where he discovered his interest in asymmetric cell division, a topic that has remained the main focus of his research ever since. In 1997, Jürgen Knoblich returned to Europe to become a group leader at the Institute of Molecular Pathology (I.M.P.) in Vienna, Austria. In 2004, he moved next door to the newly founded Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA). He became a senior scientist and was appointed deputy director of the institute in 2005 and director in 2018.
  • Plenary Lecture

    • Eran Elinav (Weizmann Institute of Science, Israel)
    • Lecture Date & Time : May 25 (Tue), 17:00-17:40, Room 101~104, 106~109
    • Title: HOST MICRO BIOME INTERACTIONS IN HEALTH AND DISEASE

    Supported by Post-Genome Research Center

    [Biography]
    Prof. Eran Elinav, M.D., Ph.D. is a professor at the Department of Immunology, Weizmann Institute of Science, and since 2019 the director of the cancer-microbiome division, at the Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany. His labs at the Weizmann Institute and DKFZ focus on deciphering the molecular basis of host-microbiome interactions and their effects on health and disease, with a goal of personalizing medicine and nutrition. Dr. Elinav completed his medical doctor’s (MD) degree at the Hebrew University of Jerusalem Hadassah Medical Center summa cum laude, followed by a clinical internship, residency in internal medicine, and a physician-scientist position at the Tel Aviv Medical Center Gastroenterology institute. He received a PhD in immunology from the Weizmann Institute of Science, followed by a postdoctoral fellowship at Yale University School of Medicine. Dr. Elinav has published more than 150 publications in leading peer-reviewed journals, including major recent discoveries related to the effects of host genetics, innate immune function and environmental factors, such as dietary composition and timing, on the intestinal microbiome and its propensity to drive multi-factorial disease. His honors include multiple awards for academic excellence including the Claire and Emmanuel G. Rosenblatt award from the American Physicians for Medicine (2011), the Alon Foundation award (2012), the Rappaport prize for biomedical research (2015) the Levinson award for basic science research (2016), and the Landau prize (2018). Since 2016 he is a senior fellow at the Canadian Institute For Advanced Research (CIFAR), since 2017 he is an elected member, European Molecular Biology Organization (EMBO) and an international scholar at the Howard Hughes Medical Institute (HHMI) and the Bill & Melinda Gates Foundation.